:root{--surface:#f8faf7;--surface-alt:#eef3ed;--surface-subtle:#f3f6f2;--border:#d8ded5;--text:#25302d;--text-strong:#101816;--muted:#60716b;--primary:#0f766e;--primary-hover:#0b5f59;--primary-text:#fff;--button-bg:#fff;--button-border:#c7d1ca;--button-hover-bg:#f6f1e8;--button-hover-border:#b7a57e;--disabled-bg:#edf0ec;--disabled-text:#95a19b;--success:#17643b;--success-bg:#e8f5ed;--success-border:#9ad0ae;--danger:#9f2f28;--danger-bg:#fff0ed;--danger-border:#e3aaa3;--base-a:#17803d;--base-c:#1d4ed8;--base-g:#b45309;--base-t:#be185d;--focus:#0f766e3d;--code-bg:#fbfcfa;--code-text:#14201d;--sans:Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;--mono:"SFMono-Regular", Consolas, "Liberation Mono", Menlo, monospace;font-family:var(--sans);color:var(--text);background:var(--surface);font-synthesis:none;text-rendering:optimizelegibility;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;font-size:16px;font-weight:400;line-height:1.45}*{box-sizing:border-box}html,body,#root{min-width:320px;height:100%;min-height:100vh;margin:0}body{overflow:hidden}@media (width<=880px){body{overflow:auto}}.app-shell{background:linear-gradient(90deg, #0f766e0e 1px, transparent 1px), linear-gradient(180deg, #246b9f0d 1px, transparent 1px), var(--surface);background-size:32px 32px,32px 32px,auto;grid-template-rows:auto auto auto minmax(0,1fr);height:100vh;min-height:0;display:grid;overflow:hidden}.top-bar{border-bottom:1px solid var(--border);background:linear-gradient(115deg, #0f766e1f, transparent 38%), linear-gradient(245deg, #b8791921, transparent 46%), var(--surface);justify-content:space-between;align-items:center;gap:24px;padding:28px 32px 22px;display:flex;position:relative;overflow:hidden}.top-bar:after{background:linear-gradient(90deg, var(--base-a), var(--base-c) 34%, var(--base-g) 67%, var(--base-t));content:"";opacity:.7;height:3px;position:absolute;bottom:-1px;left:32px;right:32px}.brand-lockup{z-index:1;align-items:center;gap:14px;min-width:0;display:flex;position:relative}.brand-logo{object-fit:contain;border-radius:8px;flex:none;width:52px;height:52px}.header-tools{z-index:1;align-items:center;gap:18px;display:flex;position:relative}.dna-mark{flex:none;width:188px;height:50px;position:relative}.dna-mark:before,.dna-mark:after{content:"";background:#0f766e57;border-radius:999px;width:182px;height:2px;position:absolute;top:23px;left:3px;transform:rotate(11deg)}.dna-mark:after{background:#246b9f47;transform:rotate(-11deg)}.dna-mark span{top:24px;left:calc(var(--i) * 13px);background:var(--base-a);opacity:.82;width:18px;height:3px;transform:translateY(calc(var(--y) * 1px)) rotate(var(--r));border-radius:999px;position:absolute}.dna-mark span:first-child{--i:0;--y:-16;--r:-20deg;background:var(--base-a)}.dna-mark span:nth-child(2){--i:1;--y:-11;--r:-14deg;background:var(--base-c)}.dna-mark span:nth-child(3){--i:2;--y:-5;--r:-8deg;background:var(--base-g)}.dna-mark span:nth-child(4){--i:3;--y:2;--r:0deg;background:var(--base-t)}.dna-mark span:nth-child(5){--i:4;--y:9;--r:9deg;background:var(--base-a)}.dna-mark span:nth-child(6){--i:5;--y:15;--r:17deg;background:var(--base-c)}.dna-mark span:nth-child(7){--i:6;--y:11;--r:14deg;background:var(--base-g)}.dna-mark span:nth-child(8){--i:7;--y:4;--r:7deg;background:var(--base-t)}.dna-mark span:nth-child(9){--i:8;--y:-3;--r:-4deg;background:var(--base-a)}.dna-mark span:nth-child(10){--i:9;--y:-10;--r:-12deg;background:var(--base-c)}.dna-mark span:nth-child(11){--i:10;--y:-16;--r:-20deg;background:var(--base-g)}.dna-mark span:nth-child(12){--i:11;--y:-10;--r:-12deg;background:var(--base-t)}.dna-mark span:nth-child(13){--i:12;--y:-3;--r:-4deg;background:var(--base-a)}.dna-mark span:nth-child(14){--i:13;--y:5;--r:8deg;background:var(--base-c)}.eyebrow{color:var(--muted);text-transform:uppercase;margin:0 0 3px;font-size:12px;font-weight:700}h1,h2{color:var(--text-strong);letter-spacing:0;margin:0}h1{font-size:34px;font-weight:720;line-height:1.08}h2{font-size:16px;font-weight:700}.status-strip{border:1px solid var(--border);max-width:520px;min-height:38px;color:var(--muted);background:var(--surface-subtle);border-radius:8px;align-items:center;gap:10px;padding:8px 12px;font-size:14px;display:inline-flex}.status-strip[data-kind=success]{color:var(--success);border-color:var(--success-border);background:var(--success-bg)}.status-strip[data-kind=error]{color:var(--danger);border-color:var(--danger-border);background:var(--danger-bg)}.control-band{border-bottom:1px solid var(--border);background:repeating-linear-gradient(90deg, transparent 0, transparent 28px, #0f766e0e 28px, #0f766e0e 30px), var(--surface-alt);grid-template-columns:auto minmax(180px,1fr) auto auto auto auto;align-items:center;gap:10px;padding:14px 32px;display:grid}.file-input{display:none}button{border:1px solid var(--button-border);min-height:38px;color:var(--text-strong);background:var(--button-bg);font:inherit;cursor:pointer;border-radius:8px;justify-content:center;align-items:center;gap:8px;padding:0 13px;font-size:14px;font-weight:650;display:inline-flex}button:hover:not(:disabled){border-color:var(--button-hover-border);background:var(--button-hover-bg)}button:focus-visible{outline:3px solid var(--focus);outline-offset:2px}button:disabled{cursor:not-allowed;color:var(--disabled-text);background:var(--disabled-bg)}.toggle-control{border:1px solid var(--button-border);min-height:38px;color:var(--text-strong);background:var(--button-bg);cursor:pointer;-webkit-user-select:none;user-select:none;border-radius:8px;justify-content:center;align-items:center;gap:8px;padding:0 12px;font-size:14px;font-weight:650;display:inline-flex}.toggle-control:hover{border-color:var(--button-hover-border);background:var(--button-hover-bg)}.toggle-control:focus-within{outline:3px solid var(--focus);outline-offset:2px}.toggle-control input{width:15px;height:15px;accent-color:var(--primary);margin:0}.primary-action{color:var(--primary-text);border-color:var(--primary);background:var(--primary)}.primary-action:hover:not(:disabled){border-color:var(--primary-hover);background:var(--primary-hover)}.icon-button{width:38px;padding:0}.file-meta{color:var(--muted);text-overflow:ellipsis;white-space:nowrap;font-size:14px;overflow:hidden}.summary-band{border-bottom:1px solid var(--border);background:#f8faf7eb;grid-template-columns:repeat(4,minmax(0,1fr));display:grid}.summary-band div{border-right:1px solid var(--border);flex-direction:column;justify-content:center;gap:4px;min-height:68px;padding:10px 32px;display:flex;position:relative}.summary-band div:before{background:var(--base-a);content:"";border-radius:999px;width:28px;height:3px}.summary-band div:nth-child(2):before{background:var(--base-c)}.summary-band div:nth-child(3):before{background:var(--base-g)}.summary-band div:nth-child(4):before{background:var(--base-t)}.summary-band div:last-child{border-right:0}.summary-band span{color:var(--muted);text-transform:uppercase;font-size:12px;font-weight:700}.summary-band strong{color:var(--text-strong);font-size:22px}.panes{grid-template-columns:minmax(0,1fr) minmax(0,1fr);min-height:0;display:grid;overflow:hidden}.pane{border-right:1px solid var(--border);grid-template-rows:auto minmax(0,1fr);min-width:0;min-height:0;display:grid;position:relative}.pane:before{background:repeating-linear-gradient(180deg, var(--base-a) 0, var(--base-a) 18px, var(--base-c) 18px, var(--base-c) 36px, var(--base-g) 36px, var(--base-g) 54px, var(--base-t) 54px, var(--base-t) 72px);content:"";opacity:.56;pointer-events:none;width:5px;position:absolute;top:49px;bottom:0;left:0}.pane:last-child{border-right:0}.pane-header{border-bottom:1px solid var(--border);background:linear-gradient(90deg, #0f766e1a, transparent 42%), var(--surface-subtle);justify-content:space-between;align-items:center;gap:16px;min-height:48px;padding:0 18px;display:flex}.pane-header span{color:var(--muted);text-overflow:ellipsis;white-space:nowrap;font-size:13px;overflow:hidden}pre{width:100%;height:100%;min-height:0;color:var(--code-text);background:linear-gradient(90deg, #246b9f0b 1px, transparent 1px), linear-gradient(180deg, #0f766e0b 1px, transparent 1px), var(--code-bg);font-family:var(--mono);text-align:left;white-space:pre;background-size:24px 24px,24px 24px,auto;margin:0;padding:18px 18px 18px 24px;font-size:13px;line-height:1.55;overflow:auto}.fasta-header{color:var(--muted);font-weight:650}.fasta-placeholder{color:var(--danger);font-weight:720}.dna-base{font-weight:720}.dna-base.base-a{color:var(--base-a)}.dna-base.base-c{color:var(--base-c)}.dna-base.base-g{color:var(--base-g)}.dna-base.base-t{color:var(--base-t)}.spin{animation:.9s linear infinite spin}@keyframes spin{to{transform:rotate(360deg)}}@media (width<=880px){.app-shell{height:auto;min-height:100vh;overflow:visible}.top-bar{flex-direction:column;align-items:stretch;padding:22px 18px 16px}.brand-logo{width:46px;height:46px}.header-tools{flex-direction:column;align-items:stretch;gap:12px}.dna-mark{width:100%;max-width:240px;height:34px}.dna-mark:before,.dna-mark:after{width:min(228px,100%);top:16px}.dna-mark span{top:17px}.status-strip{max-width:none}.control-band{grid-template-columns:1fr 1fr;padding:12px 18px}.file-meta{grid-area:1/1/auto/-1}.summary-band{grid-template-columns:repeat(2,minmax(0,1fr))}.summary-band div{border-bottom:1px solid var(--border);min-height:58px;padding:10px 18px}.summary-band div:nth-child(2n){border-right:0}.panes{grid-template-columns:1fr;min-height:0;overflow:visible}.pane{border-right:0;border-bottom:1px solid var(--border);height:420px;min-height:280px;max-height:58vh}.pane:last-child{border-bottom:0}}